Want to keep track of the largest startup funding deals in 2025 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The Crunchbase Megadeals Board.

This is a weekly feature that runs down the week’s top 10 announced funding rounds in the U.S. Check out last week’s biggest funding rounds here.

AI startups and California-based companies have been scooping up an outsized share of venture funding for a while now, and this past week was no exception. Leading the ranks was Cerebras Systems, as the AI processor developer and potential IPO candidate picked up $1.1 in fresh funding. Other large rounds went to companies in areas including AI, enterprise software, cybersecurity, blockchain and biotech.

1. Cerebras Systems, $1.1B, AI hardware: Cerebras Systems, a developer of AI processors, announced that it raised $1.1 billion in Series G funding at an $8.1 billion post-money valuation. Fidelity and Atreides Management led the financing for the Sunnyvale, California-based company, which filed to go public last year. 

2. (tied)Periodic Labs, $300M, AI: Silicon Valley-based Periodic Labs launched with $300 million in initial funding to develop AI models for science. Venture backers include Andreessen Horowitz, Felicis, DST, NVentures and Accel. 

2. (tied) Vercel, $300M, cloud infrastructure: Vercel, a developer of tools and cloud infrastructure to build websites, secured $300 million in a Series F round co-led by Accel and GIC. The financing sets a $9.3 billion valuation for the 10-year-old company. 

4. Crystalys Therapeutics, $205M, biopharma: San Diego-based Crystalys Therapeutics launched with $205 million in Series A financing to support its mission of addressing the unmet medical needs of people living with gout. Novo Holdings, SR One and Catalys Pacific led the financing.

5. Flying Tulip, $200M, blockchain: Flying Tulip, a provider of blockchain financial products, said it raised $200 million in a private funding round. Backers included CoinFund, DWF Labs, FalconX, Hypersphere, and Selini.

6. CyberCube, $180M, cybersecurity: CyberCube, a provider of cyber risk management tools, said it locked up more than $180 million in an investment from Spectrum Equity. Founded in 2015, San Francisco-based CyberCube has raised at least $285 million to date, per Crunchbase data.

7. Star Therapeutics, $125M, antibody therapies: South San Francisco, California-based Star Therapeutics, a developer of antibodies for bleeding disorders and other diseases, picked up $125 million in Series D financing co-led by Sanofi Ventures and Viking Global Investors. 

8. Eve, $103M, legal tech: Eve, a San Francisco-based AI platform for plaintiff law firms, landed $103 million in Series B funding at over a $1 billion valuation. Spark Capital led the financing, with participation from existing investors Andreessen Horowitz, Lightspeed Venture Partners, and Menlo Ventures.

9. Supabase, $100M, database technology: Postgres development platform Supabase announced that it closed on $100 million in Series E funding at a $5 billion valuation. Accel and Peak XV Partners led the financing for the five-year-old, San Francisco-based company.

10. DualEntry, $90M, accounting software: DualEntry, a provider of AI-enabled business accounting tools, secured $90 million in a Series A round that comes just 18 months after its launch.Lightspeed Venture Partners and Khosla Ventures led the financing for the New York-based company.

Illustration: Dom Guzman

Want to keep track of the largest startup funding deals in 2025 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The Crunchbase Megadeals Board.

This is a weekly feature that runs down the week’s top 10 announced funding rounds in the U.S. Check out last week’s biggest funding rounds here.

AI startups and California-based companies have been scooping up an outsized share of venture funding for a while now, and this past week was no exception. Leading the ranks was Cerebras Systems, as the AI processor developer and potential IPO candidate picked up $1.1 in fresh funding. Other large rounds went to companies in areas including AI, enterprise software, cybersecurity, blockchain and biotech.

1. Cerebras Systems, $1.1B, AI hardware: Cerebras Systems, a developer of AI processors, announced that it raised $1.1 billion in Series G funding at an $8.1 billion post-money valuation. Fidelity and Atreides Management led the financing for the Sunnyvale, California-based company, which filed to go public last year. 

2. (tied)Periodic Labs, $300M, AI: Silicon Valley-based Periodic Labs launched with $300 million in initial funding to develop AI models for science. Venture backers include Andreessen Horowitz, Felicis, DST, NVentures and Accel. 

2. (tied) Vercel, $300M, cloud infrastructure: Vercel, a developer of tools and cloud infrastructure to build websites, secured $300 million in a Series F round co-led by Accel and GIC. The financing sets a $9.3 billion valuation for the 10-year-old company. 

4. Crystalys Therapeutics, $205M, biopharma: San Diego-based Crystalys Therapeutics launched with $205 million in Series A financing to support its mission of addressing the unmet medical needs of people living with gout. Novo Holdings, SR One and Catalys Pacific led the financing.

5. Flying Tulip, $200M, blockchain: Flying Tulip, a provider of blockchain financial products, said it raised $200 million in a private funding round. Backers included CoinFund, DWF Labs, FalconX, Hypersphere, and Selini.

6. CyberCube, $180M, cybersecurity: CyberCube, a provider of cyber risk management tools, said it locked up more than $180 million in an investment from Spectrum Equity. Founded in 2015, San Francisco-based CyberCube has raised at least $285 million to date, per Crunchbase data.

7. Star Therapeutics, $125M, antibody therapies: South San Francisco, California-based Star Therapeutics, a developer of antibodies for bleeding disorders and other diseases, picked up $125 million in Series D financing co-led by Sanofi Ventures and Viking Global Investors. 

8. Eve, $103M, legal tech: Eve, a San Francisco-based AI platform for plaintiff law firms, landed $103 million in Series B funding at over a $1 billion valuation. Spark Capital led the financing, with participation from existing investors Andreessen Horowitz, Lightspeed Venture Partners, and Menlo Ventures.

9. Supabase, $100M, database technology: Postgres development platform Supabase announced that it closed on $100 million in Series E funding at a $5 billion valuation. Accel and Peak XV Partners led the financing for the five-year-old, San Francisco-based company.

10. DualEntry, $90M, accounting software: DualEntry, a provider of AI-enabled business accounting tools, secured $90 million in a Series A round that comes just 18 months after its launch.Lightspeed Venture Partners and Khosla Ventures led the financing for the New York-based company.

Illustration: Dom Guzman